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Information about Sabril Granules (Vigabatrin)
Sabril Granules, containing the active ingredient vigabatrin, are an oral form of the medication used to treat specific types of epilepsy, including refractory complex partial seizures and infantile spasms. This formulation provides a convenient option for patients who have difficulty swallowing tablets, particularly young children or individuals who require precise, flexible dosing. Vigabatrin works by increasing the levels of gamma-aminobutyric acid (GABA) in the brain, which helps to control seizure activity.
Product Highlights
- Sabril Granules are used in adults and children whose complex partial seizures are not well controlled by other medications.
- It is used in infants (typically from 1 month to 2 years of age) to treat infantile spasms, a rare but serious condition that causes sudden muscle spasms.
Key Ingredient
Key Benefits
- The granule formulation allows for easier and more adjustable dosing, particularly useful for young children or those with difficulty swallowing tablets.
- It is effective in treating drug-resistant complex partial seizures and infantile spasms, offering an alternative when other treatments fail.
- The granules can be mixed with a liquid, making it easier for patients who need a non-pill form of medication.
Direction of Use
- Sabril Granules are typically mixed with a small amount of liquid or soft food, and the prescribed dose depends on the patient’s weight, age, and medical condition.
- The dosage is carefully adjusted based on the infant's weight and clinical response.
The specific dosage and frequency of administration should be prescribed by a healthcare provider.
Safety Concerns
- A serious and potentially irreversible side effect of vigabatrin is vision loss. Regular eye exams are essential during treatment to monitor for any changes in vision.
- Vigabatrin may cause mood changes, depression, or other psychiatric symptoms, particularly in adults.
- Some patients may experience memory problems or drowsiness, which can affect their ability to function.
- As with other anticonvulsants, vigabatrin may increase the risk of suicidal thoughts or behaviors. Patients should be monitored for signs of depression or suicidal ideation.
- Vigabatrin can interact with other medications, particularly other anticonvulsants, and may require adjustments to the treatment regimen.
Avoid Sabril Granules (Vigabatrin) If
- Sabril Granules should be avoided in patients with pre-existing severe vision problems, as it can worsen or cause irreversible vision loss.
- Patients with a known allergy to vigabatrin should not use this medication.
- Those with a history of severe psychiatric disorders or depression may need to avoid Sabril Granules due to the risk of psychiatric side effects.
- The use of Sabril Granules during pregnancy should be limited to situations where the benefits outweigh the risks, and it is typically not recommended for breastfeeding without medical supervision.