Information about Stalevo (Entacapone / Levodopa / Carbidopa)
Stalevo is a prescription medication that combines three active ingredients: entacapone, levodopa, and carbidopa. It is mainly used to treat Parkinson's disease. The combination of these three ingredients works together to increase the effectiveness of levodopa, which helps improve the symptoms of Parkinson’s disease such as tremors, stiffness, and slowness of movement. Entacapone works by inhibiting an enzyme that breaks down levodopa, allowing it to remain active in the body for a longer period.
Product Highlights
- To manage the symptoms of Parkinson’s disease, especially in patients who experience "end-of-dose wearing off" or when levodopa alone is not sufficient to control symptoms.
- Specifically helps in controlling motor fluctuations, including periods when the patient experiences a return of symptoms (off periods) between doses of levodopa.
Key Ingredient
- Entacapone
- Levodopa
- Carbidopa
Key Benefits
- The combination provides better control of Parkinson's disease symptoms, including tremors, stiffness, and slowness of movement.
- Helps minimize fluctuations in symptom control that can occur between doses of levodopa.
- The three medications in one tablet reduce the need for multiple doses of separate drugs, improving patient adherence to treatment.
- The addition of entacapone improves the effectiveness of levodopa by preventing its premature breakdown.
Direction of Use
- The dosage of Stalevo will vary based on the severity of Parkinson's disease and the patient’s response to treatment. The typical starting dose is 1 tablet taken 3 to 4 times per day, with adjustments made by the healthcare provider.
- Stalevo can be taken orally, with or without food. It is important to follow the prescribed dosing schedule and avoid taking it late in the day to reduce the risk of sleep disturbances.
- Patients should have regular follow-ups with their healthcare provider to adjust the dose as needed and monitor for side effects.
Safety Concerns
- Stalevo may cause changes in blood pressure, especially during dose adjustments. Regular monitoring of blood pressure is essential.
- Long-term use of levodopa may cause involuntary movements (dyskinesia). If this occurs, your healthcare provider may adjust the dose or consider other treatment options.
- Stalevo can affect mood, causing symptoms such as depression, confusion, or hallucinations. These should be reported immediately.
- Entacapone can affect liver function, so regular liver function tests are recommended.
- Some patients may develop compulsive behaviors, such as gambling or hypersexuality, while taking medications like Stalevo.
- Stalevo may interact with other medications, including certain antidepressants, antipsychotics, and blood pressure medications. Make sure to inform your healthcare provider about all the medications you are taking.
- Some patients may experience drowsiness or sudden sleep onset, which can be dangerous when operating vehicles or machinery.
Avoid Stalevo (Entacapone / Levodopa / Carbidopa) If
- If you have known allergies to entacapone, levodopa, carbidopa, or any other ingredients in the formulation.
- Stalevo may increase the pressure in the eyes, which can be dangerous for individuals with glaucoma.
- Levodopa has been associated with an increased risk of melanoma in some patients.
- If you have heart disease or irregular heart rhythms, Stalevo should be used with caution.
- Stalevo should only be used during pregnancy or breastfeeding if the potential benefits outweigh the risks. Consult your doctor before use.
- Patients with a history of psychosis, hallucinations, or other serious mental health issues should avoid using Stalevo without medical supervision.
