Neupro patch (Rotigotine)

Prescription Neupro patch (rotigotine) is a medicine used in the treatment of Parkinson's disease and moderate to severe restless leg syndrome (RLS).

Neupro provides the transdermal delivery of rotigotine, which stimulates dopamine receptors in the brain, reducing muscle activity associated with symptoms of RLS and improves Parkinons's disease where dopamine activity is too low.

Neupro patches are applied once per day.  Neupro is available from 1mg, 2mg, 3mg, 4mg, 6mg and 8mg patches, providing 24 hour medicine delivery.

For the treatment of RLS, Neupro reduces discomfort, and sleep disturbances. Neupro improves mobility and lessens frequency and severity of your RLS symptoms.  After 6 months, almost 1 in 4 patients were completely symptom free with Neupro. The dose of Neupro in RLS is usually 1mg, 2mg, or 3mg delivered by patch daily. Doses of Neupro may be adjusted weekly by your physician.

For the treatment of Parkinson's disease, Neupro can provide you less "off" time and more "on" time to give better control of the disease. Neupro improves symptoms including tremors, stiffness, slowness, and balance to improve your daily life. Neupro may be given alone or added to existing therapy.

Neupro patches are applied once daily at the same time each day. Any time of day will work as long as you are consistent.  Because Neupro is a patch, food will not interfere with your dose as there is no pill to swallow.

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Information about Neupro patch (Rotigotine)

Neupro is a transdermal patch containing the active ingredient rotigotine, which is a non-ergoline dopamine agonist used in the treatment of Parkinson’s disease and restless legs syndrome (RLS). The patch delivers rotigotine through the skin, providing continuous medication release over a 24-hour period.

Product Highlights

• Neupro (rotigotine) is primarily used to treat:
• Neupro is indicated for the treatment of Parkinson’s disease, helping to control symptoms such as tremors, stiffness, and slowness of movement by stimulating dopamine receptors in the brain.
• The patch is also prescribed for the treatment of moderate-to-severe primary restless legs syndrome, which is characterized by an uncontrollable urge to move the legs, often accompanied by discomfort, particularly at night.

Key Ingredient

• Rotigotine

Key Benefits

• The Neupro patch provides a continuous release of rotigotine over a 24-hour period, offering consistent symptom control without the need for multiple daily doses.
• By stimulating dopamine receptors, rotigotine can improve motor function in patients with Parkinson's disease, leading to better movement, reduced tremors, and improved quality of life.
• Neupro can alleviate the discomfort associated with restless legs syndrome, reducing the urge to move the legs and helping improve sleep quality.
• Unlike oral dopamine agonists, the patch bypasses the gastrointestinal tract, reducing the risk of nausea and vomiting, which are common side effects of oral medications.
• The once-daily application increases patient adherence to treatment compared to medications that require more frequent dosing.

Direction of Use

• The Neupro patch should be applied once daily to a clean, dry, and non-irritated area of skin. It is typically placed on the upper arm, abdomen, thigh, or hip. The patch should be applied to a different site each day to avoid skin irritation.
• To avoid skin irritation, the patch should not be applied to the same site for consecutive days.
• The patch should be worn for 24 hours, after which a new patch should be applied to a different site.
• The dosage of Neupro may be gradually increased depending on the patient’s response and tolerability. It is essential to follow the healthcare provider's guidance.

Safety Concerns

• Some individuals may experience irritation, redness, or rash at the patch site. It is important to rotate application sites to minimize this risk.
• Rotigotine can cause drowsiness, dizziness, or sudden onset of sleep. Patients should use caution when driving or performing activities that require full alertness.
• A common side effect of rotigotine is low blood pressure, which can cause dizziness, fainting, or lightheadedness, especially when standing up quickly. This is more common when starting treatment or increasing the dose.
• In some patients, rotigotine can cause hallucinations, confusion, or other psychiatric symptoms, especially in older adults or those with preexisting mental health conditions.
• Dopamine agonists like rotigotine have been associated with impulse control disorders such as compulsive gambling, eating, or sexual behaviors. Patients should be carefully observed for any behavioral changes.
• Abrupt discontinuation of Neupro or a sudden dose reduction can lead to withdrawal symptoms, including anxiety, confusion, or sleep disturbances. Tapering should be carried out with medical supervision.
• Neupro is not recommended during pregnancy unless the potential benefits outweigh the risks to the fetus. It should also be avoided while breastfeeding, as it may be passed into breast milk.

Avoid Neupro Patch (Rotigotine) If

• If you have a known allergy to rotigotine or any of the components in the Neupro patch (e.g., adhesives or preservatives), you should avoid using this medication.
• If you have a history of severe low blood pressure (hypotension), especially in conjunction with standing or sitting up quickly, Neupro may not be appropriate for you.
• Neupro should not be used during pregnancy unless the potential benefit outweighs the risks. Always discuss potential risks with your doctor if you are pregnant or planning to become pregnant.
• If you have active skin conditions, rashes, or infections at the site of patch application, Neupro should be avoided, as it may cause further irritation or hinder proper absorption.
• If you have a history of psychosis, hallucinations, or severe mental disorders, Neupro may not be suitable due to the potential for worsening psychiatric symptoms.
• If you have had previous adverse reactions to dopamine agonists, such as rotigotine or other similar medications, you should avoid using Neupro.