Mavenclad (Cladribine)

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Brand Name : Mavenclad

Marketing Authorization Holder : Merck Sharp & Dohme

Prescription Required

 
 
No Generic Medicine available for this medicine.

Product Details

Mavenclad

Prescription Mavenclad contains cladribine, a cytotoxic medicine which works mostly on the cells of the immune system called lymphocytes. In multiple sclerosis, these lymphocytes are involved in the inflammation process, which destroys the protective sheath around nerves. By killing lymphocytes Mavenclad treats multiple sclerosis, reducing symptom flare ups and slowing down the progression of the disease. Mavenclad is a disease modifying drug.

Mavenclad is taken exactly as your physicians prescribes, usually in 2 treatment courses 12 months apart. Mavenclad dose is based on patient size and weight as well as other considerations. Usually Mavenclad is taken for 5 days in a row in a first month and again in the second month then repeated one year later. Mavenclad can reduce relapse by about 50%.

Mavenclad can reduce your white blood cell count and activate herpes virus in the form of shingles and oral herpes.

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Information about Mavenclad (Cladribine)

Mavenclad is an oral medication that contains cladribine, a selective immunosuppressive agent. It is primarily used in the treatment of multiple sclerosis (MS), specifically for relapsing forms of the disease.

Product Highlights

  • Specifically indicated for the treatment of relapsing forms of multiple sclerosis, including relapsing-remitting MS and active secondary progressive MS.

Key Ingredient

  • Cladribine

Key Benefits

  • Proven to reduce the frequency of MS relapses and slow the progression of disability in patients.
  • Limited treatment courses per year improve adherence and reduce the burden of daily medication.
  • Selectively targets certain immune cells, which may help preserve overall immune function compared to broader immunosuppressants.

Direction of Use

  • Take Mavenclad as prescribed by your healthcare provider. Typically, two treatment courses are given per year, each consisting of a specific number of days of treatment.
  • Can be taken with or without food; however, it is important to maintain consistency in how it is taken.
  • Regular follow-up appointments and monitoring for side effects are essential.

Safety Concerns

  • Common side effects may include headache, nausea, fatigue, and increased risk of infections due to immunosuppression.
  • Regular blood tests are required to monitor lymphocyte counts and liver function.
  • Increased risk of serious infections, particularly in patients with pre-existing conditions or those on other immunosuppressive therapies.

Avoid Mavenclad (Cladribine) If

  • History of hypersensitivity to cladribine or any of the formulation components.
  • Patients with active infections or a history of recurrent infections should avoid use.
  • Not recommended for individuals with significant liver dysfunction.


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