Prescription Pulmozyme nebules contain dornase alfa used along with other therapies to improve pulmonary function in cystic fibrosis. Pulmozyme is a copy of the protein DNase which is naturally occurring in the body. Pulmozyme breaks down the thick mucus in the lungs to help the lungs work better.
Pulmozyme is prescribed to adults and children 5 years of age and older. Pulmozyme is a once or twice daily therapy. Lower doses are often reserved for children.
Pulmozyme nebules are inhaled as nebules using standard nebuliser devices available in the market. When preparing your nebuliser, be sure not to mix Pulmozyme with other medicines or liquids. Do not store or keep any excess Pulmozyme medicines which may remain once the nebule is used. Be certain that the nebuliser is clean prior to use, then open and pour the contents of one nebule into the nebuliser. Follow the instructions in the Pulmozyme package and discuss any issues with your physician or caregiver.
Pulmozyme is stored and shipped in refrigerated conditions in the original packaging protected from light. Pulmozyme may be used if left out of the refrigerator for less than 24 hours.
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Information about Pulmozyme (Dornase alfa)
Pulmozyme is a prescription medication used primarily for individuals with cystic fibrosis (CF). It is a synthetic version of the human enzyme deoxyribonuclease (DNase), created to break down DNA in the mucus that builds up in the lungs of individuals with CF. This action helps to reduce the viscosity (thickness) of the mucus, improving lung function and decreasing the risk of lung infections.
Product Highlights
- Specifically for individuals with this genetic condition who have moderate to severe lung function impairment. It helps enhance lung function and decrease the occurrence of respiratory infections.
- Pulmozyme helps to thin mucus and make it easier to clear from the lungs, improving breathing.
Key Ingredient
Key Benefits
- By reducing mucus thickness, Pulmozyme enhances airway clearance, which can lead to better lung function.
- Regular use of Pulmozyme has been shown to decrease the frequency of respiratory infections, leading to fewer flare-ups of CF-related symptoms.
- By improving lung function and reducing infections, Pulmozyme can help people with CF maintain better overall health and a higher quality of life.
Direction of Use
- Pulmozyme is typically used once daily, though some patients may require more frequent use as advised by a healthcare provider.
- It is delivered through a nebulizer, which converts the liquid solution into a fine mist for inhalation.
- The suggested dose is 2.5 mg of dornase alfa in 2.5 mL of solution.
- Patients should follow their healthcare provider’s instructions for use and ensure that their nebulizer and mask or mouthpiece are clean and functioning properly.
Safety Concerns
- Inhalation of Pulmozyme may cause throat irritation, hoarseness, or voice changes.
- Some patients may experience an allergic reaction to the medication, which can manifest as rash, hives, difficulty breathing, or swelling. An allergic reaction requires immediate medical attention.
- Regular monitoring of lung function is important as the medication may not be suitable for all patients, especially those with severe pulmonary conditions.
Avoid Pulmozyme (Dornase alfa) If
- Patients who have known hypersensitivity or an allergy to dornase alfa or any of its components should avoid using Pulmozyme.
- People with a history of severe respiratory conditions like pulmonary hemorrhage (bleeding in the lungs) should not use this medication unless prescribed by a doctor after careful evaluation.
- Though Pulmozyme is sometimes prescribed for children with CF, it is typically not recommended for those under 5 years old unless directed by a physician.
This product requires special packaging to maintain its integrity during the shipping process. DO NOT USE THIS MEDICATION if the attached temperature indicator shows that the medication was exposed to temperatures below 2 degrees or above 8 degrees Celsius, and contact the pharmacy immediately.
