Cymbalta (Duloxetine)

Cymbalta 20mg and 40mg are called Yentreve in UK.

Information about Cymbalta (Duloxetine)

Cymbalta is a brand name for duloxetine, a prescription medication that belongs to the class of drugs known as serotonin-norepinephrine reuptake inhibitors (SNRIs). It is primarily used to treat various mood and anxiety disorders by increasing levels of serotonin and norepinephrine in the brain, which helps regulate mood, pain, and anxiety.

Product Highlights

• Major Depressive Disorder (MDD): Used to treat symptoms of depression in adults.
• Generalized Anxiety Disorder (GAD): Helps manage chronic anxiety and associated symptoms.
• Provides relief from pain caused by diabetic neuropathy.
• Used to manage widespread pain and tenderness associated with fibromyalgia.
• Helps alleviate pain related to conditions such as osteoarthritis and chronic lower back pain.

Key Ingredient

• Duloxetine

Key Benefits

• Assists in boosting mood and relieving anxiety symptoms.
• Provides relief from certain types of chronic pain, including neuropathic and musculoskeletal pain.
• Works on both serotonin and norepinephrine, which can be beneficial for treating a range of symptoms.
• Available in capsule form, usually taken once or twice daily.

Direction of Use

• Typically given once or twice a day, either with or without food. The dosage is tailored to the specific condition and the patient’s response.
• Starting Dose: Often begins at a lower dose, which may be gradually increased based on efficacy and tolerability.
• Missed Dose: If a dose is missed, take it as soon as possible unless it's almost time for the next dose. Refrain from taking an additional dose to replace a missed one.

Safety Concerns

• May include nausea, dry mouth, drowsiness, fatigue, constipation, and loss of appetite.
• Rare but may include serotonin syndrome (symptoms include agitation, hallucination, fever, excessive sweating, and muscle spasms), increased risk of suicidal thoughts or behavior in younger patients, liver problems, and high blood pressure.
• Regular follow-up with a healthcare provider is necessary to monitor for side effects, efficacy, and any potential interactions with other medications.

Avoid Cymbalta (Duloxetine) If

• History of hypersensitivity or allergic reactions to duloxetine or any other ingredients in the formulation.
• Due to the risk of liver damage and potential for exacerbating liver conditions.
• Within 14 days of using MAOIs, due to risk of serious drug interactions.
• Caution is advised, and dose adjustments may be required.
• Use during pregnancy or lactation should be considered carefully, weighing the potential benefits against risks, and under the guidance of a healthcare provider.