Avalide (Irbesartan / HCTZ)

Avalide is called Co-Aprovel in Europe.

Information about Avalide (Irbesartan / HCTZ)

Avalide is used to treat high blood pressure (hypertension). It helps manage blood pressure levels and reduce the risk of stroke, heart attack, and kidney problems associated with hypertension. It may also be used in patients with heart conditions or those at risk of cardiovascular events.

Avalide is a combination medication of irbesartan, an angiotensin II receptor antagonist, & hydrochlorothiazide, a thiazide diuretic, indicated for hypertension:

• In patients not adequately controlled with monotherapy. 
• As initial therapy in patients need multiple drugs to achieve their blood pressure goals.

Product Highlights

• Avalide is a fixed-dose combination of Irbesartan, an angiotensin II receptor blocker (ARB), and Hydrochlorothiazide, a thiazide diuretic.
• The combination works synergistically to lower blood pressure by relaxing blood vessels and increasing urine output, which helps reduce blood volume.
• It simplifies treatment by combining two effective drugs into a single tablet.

Key Ingredients

• Irbesartan
• Hydrochlorothiazide (HCTZ)

Key Benefits

• Provides substantial reduction in blood pressure, often more effectively than a single medication alone.
• Helps decrease the risk of stroke, heart attack, and heart failure.
• Simplifies medication regimen, improving patient adherence to treatment.

Direction For Use

• Avalide is typically taken once daily, with or without food. The exact dosage will be determined by a healthcare provider based on individual needs and response to treatment.

Safety Concern

• Common side effects include dizziness, fatigue, headache, and gastrointestinal symptoms. More serious side effects can include electrolyte imbalances, kidney dysfunction, or severe allergic reactions.
• Monitoring of blood pressure, kidney function, and electrolyte levels is recommended during treatment.

Avoid Avalide (Irbesartan / HCTZ) If

• You are allergic to Irbesartan, Hydrochlorothiazide, or any other component of the medication.
• Severe kidney disease or conditions that impair kidney function.
• It should be avoided during pregnancy as it can harm the fetus. Women who are pregnant or planning to become pregnant should discuss alternative treatments option with their healthcare provider.
• Conditions like severe liver disease, certain types of glaucoma (sulfa allergies), or a history of severe reactions to diuretics or ARBs.