Information about Zyloprim (Allopurinol)
Zyloprim (Allopurinol) is a medication used primarily to lower uric acid levels in the body. It works by blocking the enzyme xanthine oxidase, which plays a key role in the production of uric acid. By reducing uric acid levels, it helps prevent gout attacks and the formation of uric acid kidney stones.
Product Highlights
- Zyloprim is used to prevent gout attacks by lowering uric acid levels in the blood and tissues.
- It is used for managing high levels of uric acid, which may occur in conditions like gout or as a side effect of certain treatments, such as chemotherapy.
- It helps prevent the formation of uric acid kidney stones.
- Zyloprim is used to prevent or treat elevated uric acid levels due to rapid cell breakdown from chemotherapy.
Key Ingredient
Key Benefits
- By lowering uric acid levels, Zyloprim helps reduce the frequency and severity of gout attacks.
- It prevents the formation of uric acid crystals in the kidneys, reducing the risk of kidney stones.
- Zyloprim is also effective in preventing hyperuricemia caused by rapid cell breakdown, such as after chemotherapy.
- Allopurinol is generally well-tolerated when taken as prescribed.
Direction of Use
- The typical starting dose is 100 mg to 300 mg daily, depending on the severity of the condition and individual response. It can be adjusted based on the patient's uric acid levels.
- The tablets should be taken with food to minimize gastrointestinal upset. The dose may be divided throughout the day (e.g., in one or two doses) for better tolerance.
- It's essential to drink plenty of fluids while on Zyloprim to prevent the formation of kidney stones.
- Regular blood tests may be needed to monitor uric acid levels and kidney function.
Safety Concerns
- Serious skin reactions like rash or Stevens-Johnson syndrome can occur, particularly in the early stages of treatment.
- Allopurinol may affect liver and kidney function, so regular monitoring of liver enzymes and renal function is recommended during treatment.
- Some people may experience allergic reactions such as fever, chills, and swelling. If these occur, medical attention should be sought.
- Rarely, allopurinol may cause a reduction in blood cell counts, leading to conditions such as anemia, leucopenia, or thrombocytopenia.
- Nausea, vomiting, and diarrhea may occur in some individuals.
Avoid Zyloprim (Allopurinol) If
- If you have a known hypersensitivity to allopurinol or any of its components, you should avoid taking Zyloprim.
- Zyloprim should not be used in individuals with severe kidney or liver dysfunction without close medical supervision.
- Allopurinol is not recommended during an acute gout flare-up, as it can worsen the symptoms in the short term. It should be used only for long-term prevention of gout.
- Zyloprim should be used with caution in pregnant or breastfeeding women, only if the benefits outweigh the risks, and under the guidance of a healthcare professional.
