Information about Symmetrel (Amantadine)
Symmetrel (Amantadine) is an antiviral and dopaminergic agent primarily used to treat certain viral infections and neurological disorders. It is commonly prescribed for the prevention and treatment of influenza A and for managing symptoms of Parkinson's disease and drug-induced extrapyramidal symptoms. Amantadine works by inhibiting the replication of the influenza A virus and by increasing the release of dopamine in the brain, which helps improve motor function in Parkinson's disease.
Product Highlights
- Symmetrel can help prevent and treat symptoms of influenza A by inhibiting the replication of the virus.
- It is used as an adjunct treatment for Parkinson's disease to help manage motor symptoms by enhancing dopamine activity in the brain.
- Amantadine can be used to treat drug-induced movement disorders, such as tremors or rigidity caused by antipsychotic medications.
Key Ingredient
Key Benefits
- Symmetrel can reduce the severity and duration of flu symptoms and help prevent influenza A infections in high-risk individuals.
- By increasing dopamine release, Symmetrel can improve motor function, such as reducing tremors, rigidity, and bradykinesia in Parkinson's patients.
- Symmetrel helps to relieve extrapyramidal symptoms (such as tremors and rigidity) caused by the use of antipsychotic medications.
- It may provide neuroprotective effects, offering additional benefits in Parkinson’s disease by slowing the progression of the disease.
Direction of Use
- Symmetrel is taken orally, either as tablets or in liquid form.
The usual dose for adults varies depending on the condition:
For Influenza A: 200 mg daily, divided into 1 or 2 doses for treatment or prevention.
For Parkinson’s Disease: Typically starts with a lower dose of 100 mg daily, gradually increasing as directed by the healthcare provider.
For Drug-Induced Extrapyramidal Symptoms: The dose may vary but is typically 100 mg twice daily.
- If you miss a dose, take it as soon as you remember, unless it's almost time for your next dose. Do not double the dose.
Safety Concerns
- Possible side effects may include dizziness, trouble sleeping, nausea, dry mouth, constipation, and headaches.
- Serious side effects may include hallucinations, confusion, swelling of the ankles, heart problems (e.g., arrhythmia), and suicidal thoughts. Patients should report any unusual psychiatric symptoms to their doctor.
- Amantadine can affect liver and kidney function, so it is important to monitor liver enzymes and renal function regularly during treatment.
- Some patients may experience changes in mood or mental status, including anxiety, depression, and confusion.
- Although rare, amantadine can increase the risk of seizures, especially in individuals with a history of seizures.
Avoid Symmetrel (Amantadine) If
- If you are allergic to Amantadine or any components of the medication, you should avoid using Symmetrel.
- Patients with severe kidney or liver dysfunction should avoid Symmetrel or use it under careful medical supervision due to the potential for increased side effects.
- If you have a history of seizures, you should not use Symmetrel, or it should be used with caution.
- Symmetrel is classified as a pregnancy category C drug, meaning it should only be used if the potential benefits outweigh the risks. It is not recommended during breastfeeding unless advised by a healthcare provider.
- Symmetrel may cause or exacerbate psychiatric symptoms such as hallucinations, confusion, or suicidal thoughts. It should be avoided in individuals with a history of severe psychiatric disorders unless specifically recommended by a healthcare professional.
