Dificid (Fidaxomicin)

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Brand Name : Dificid

Marketing Authorization Holder : Astellas

Prescription Required

 
 
No Generic Medicine available for this medicine.

Product Details

Dificid

Dificid is called Dificlir in Europe.

Non-english packaging is often present for European medicines- English label and English insert included. Plan in advance - allow us 7 days to ship this brand name medicine.

According to the European Medicines Agency, brand name Dificlir originating from Europe is manufactured at the following site(s):Almac Pharma Services Limited Seagoe Industrial Estate, Portadown, Craigavon, BT63 5UA, United KingdomTillotts Pharma GmbH Warmbacher Strasse 80 79618 Rheinfelden Germany

Information about Dificid (Fidaxomicin)

Dificid, containing Fidaxomicin, is an oral antibiotic used to treat infections caused by the bacterium Clostridium difficile. It is specifically designed to target and eliminate C. difficile bacteria, which are known to cause Clostridium difficile infection (CDI), often associated with antibiotic use and resulting in symptoms like severe diarrhea.

Product Highlights

  • Dificid is primarily indicated for the treatment of CDI, a condition characterized by severe diarrhea and colitis caused by Clostridium difficile bacteria.

Key Ingredient

  • Fidaxomicin

Key Benefits

  • Specifically targets Clostridium difficile, reducing the likelihood of disrupting the normal intestinal flora and minimizing the risk of relapse.
  • Demonstrated efficacy in treating CDI and reducing recurrence compared to some other antibiotics.
  • Limited absorption into the bloodstream, which focuses its action in the gut and helps reduce systemic side effects.

Direction of Use

  • The standard dosage is 200 mg taken twice daily for 10 days.
  • Tablets should be swallowed whole with water. They can be taken regardless of food intake.
  • Follow the prescribed course of treatment exactly as directed by a healthcare provider, even if symptoms improve before the end of the course.

Recommended Dosage of DIFICID in Pediatric Patients, Based on Weight:

Body WeightDose Administered Twice Daily
4 kg to less than 7 kg80 mg
7 kg to less than 9 kg120 mg
9 kg to less than 12.5 kg160 mg
12.5 kg and above200 mg

Safety Concerns

  • Common side effects may include nausea, vomiting, abdominal pain, and diarrhea. Serious side effects are rare but could include severe allergic reactions.
  • Regular monitoring for potential side effects is recommended, especially if other medications are being taken concurrently.

Avoid Dificid (Fidaxomicin) If

  • You have a known allergy or hypersensitivity to Fidaxomicin or any of its components.
  • Use with caution in patients with severe liver impairment, as it may affect drug metabolism.
  • The safety of Fidaxomicin during pregnancy has not been well established. Use it during pregnancy only if clearly needed and prescribed by a healthcare provider.
  • The safety of Fidaxomicin during breastfeeding is not well-established. If you are breastfeeding, consult your healthcare provider before using it.


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