Aptivus (Tipranavir)

Prescription Aptivus is used as a combination therapy with ritonavir 200mg (and other HIV medicines) to treat patients infected with HIV-1, a virus that causes AIDS. Aptivus is given to patients 2 years old and older who have experience with anti-HIV medicines or are infected with resistant strains of HIV-1. 

Aptivus is used when the patient does not have another treatment option. These patients have already tried other antiviral medicines in the same class.

Aptivus works by blocking an enzyme, protease which is needed for HIV virus reproduction. By blocking this enzyme, the virus cannot reproduce normally so the infection cannot spread as easily. By adding Ritonavir (another protease inhibitor) the effect of Aptivus is boosted because Aptivus will not break down as easily and blood levels will increase. By taking these 2 medicines together, you are able to take a lower dose of Aptivus, reducing side effects of the medicine.

The recommended dose of Aptivus for patients 12 years and older is 500mg twice daily (4 capsules daily).  Children under 12 years take the oral solution (also available with us). Take Aptivus with ritonavir with food only. Follow your doctors directions and the read the package insert.

Aptivus is not a cure for HIV or AIDS but will delay the disease progression and the damage done to the immune system and subsequent infections and conditions associated with AIDS.

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Information about Aptivus (Tipranavir)

Aptivus, with the active ingredient tipranavir, is primarily used as part of an antiretroviral therapy regimen to manage HIV-1 infection. Tipranavir works by inhibiting the action of the HIV-1 protease enzyme, which is crucial for the virus's replication process.

It is prescribed for patients who are already on other HIV medications and have not achieved adequate viral suppression or in cases where the virus has developed resistance to other treatments.

Product Highlights

• Aptivus is brand name of medicine & generic name is Tipranavir.
• Oral capsules, typically taken with food.
• Part of medicine class protease inhibitor (PI).
• Approved by the FDA for use in HIV-1 infection in combination with other antiretroviral drugs.

Key Ingredients

• Tipranavir
• Dehydrated alcohol
• Polyoxyl 35 castor oil
• Propylene glycol
• Mono/diglycerides 
• Gelatin

Key Benefits

• Helps reduce the amount of HIV in the blood, improving immune function and slowing disease progression.
• Particularly useful in patients with HIV strains that have developed resistance to other protease inhibitors.
• Used in combination with other antiretrovirals to enhance overall effectiveness.

Direction For Use

• Typically, the standard dosage is 500 mg twice daily, taken with food. However, the specific dosage can vary based on individual patient needs and other medications being taken.
• Take Aptivus exactly as prescribed by your healthcare provider. Do not skip doses or stop taking the medication without consulting your doctor.

Safety Concern

• Common side effects nausea, diarrhea, headache, fatigue, and rash.
• Liver problems (e.g., hepatitis), bleeding problems, and an increased risk of developing diabetes or hyperlipidemia (elevated cholesterol levels).
• Routine liver function tests and blood tests are often required to monitor for side effects.

Avoid Aptivus (Tipranavir) If

• You have severe liver disease or active liver infection (e.g., hepatitis B or C) unless advised by your healthcare provider.
• You have a hypersensitivity or allergy to tipranavir or any other components of the medication.
• Be cautious if you are taking certain medications that may interact with Aptivus, including certain antiepileptic drugs, antimycobacterial drugs, and other protease inhibitors.