Information about Sustiva (Efavirenz)
Sustiva is a prescription medication that contains efavirenz, a non-nucleoside reverse transcriptase inhibitor (NNRTI) used to treat HIV (human immunodeficiency virus) infection. It works by blocking the action of reverse transcriptase, an enzyme critical for HIV replication. By blocking this enzyme, efavirenz helps to reduce the amount of virus in the blood, supporting the immune system in controlling HIV.
Product Highlights
- Sustiva is mainly used to treat HIV-1 infection as part of a combination therapy with other antiretroviral medications. It is not a cure for HIV but helps manage the virus by reducing its ability to replicate.
- It is commonly used in combination with other medications to manage HIV infection.
Key Ingredient
Key Benefits
- Efavirenz helps lower the amount of HIV in the blood, making the infection more manageable.
- By controlling viral replication, it helps maintain or improve the functioning of the immune system.
- Sustiva is typically taken once daily, improving ease of adherence to the treatment regimen.
- When used with other antiretroviral drugs, efavirenz can be highly effective in managing HIV infection.
Direction of Use
- The standard dose for adults is 600 mg taken once daily. The dose may vary depending on individual circumstances and doctor recommendations.
- Take Sustiva on an empty stomach, preferably at bedtime, to reduce the likelihood of side effects like dizziness and drowsiness.
- It is essential to take Sustiva exactly as prescribed, at the same time each day, and not to miss doses to maintain the effectiveness of the treatment.
- If you miss a dose, take it as soon as you remember, unless it's almost time for your next dose. Do not take two doses at the same time to compensate for a missed dose.
Safety Concerns
- Common side effects of Sustiva include dizziness, headache, nausea, trouble sleeping, and rash. Serious side effects can include liver problems, severe skin reactions, and changes in mood or behavior.
- Efavirenz has been associated with neuropsychiatric effects such as depression, vivid dreams, or suicidal thoughts. Patients should be monitored for these effects.
- Efavirenz can cause liver damage, so liver function tests should be performed before starting treatment and periodically thereafter.
- Efavirenz can interact with other medications, including certain antifungals, anticonvulsants, and antituberculosis drugs. It is crucial to inform the doctor about all the medications you are taking.
- Efavirenz is contraindicated during pregnancy, especially in the first trimester, as it may harm the developing fetus. Women of childbearing age should use effective contraception while taking Sustiva.
Avoid Sustiva (Efavirenz) If
- You are allergic to efavirenz or any other ingredients in Sustiva.
- You are pregnant or planning to become pregnant, particularly during the first trimester.
- You have a history of severe liver disease (e.g., cirrhosis).
- You have a history of severe mental health conditions such as depression, suicidal thoughts, or psychosis.
- You are taking medications that may interact with Sustiva, such as certain anticonvulsants, antifungals, or other antiretrovirals, unless directed otherwise by a healthcare provider.
- You have a history of alcohol or drug abuse, as these can increase the risk of side effects.
