Information about Videx (Didanosine)
Videx is the brand name for Didanosine, an antiviral medication used primarily to treat HIV/AIDS. It is a nucleoside reverse transcriptase inhibitor (NRTI) that works by inhibiting the enzyme reverse transcriptase, which is essential for the replication of the HIV virus. By blocking this enzyme, Videx helps to slow the progression of HIV infection and lower the amount of HIV in the body.
Product Highlights
- As part of a combination antiretroviral regimen for the treatment of HIV infection in adults and pediatric patients.
- Videx is not used alone but as part of combination therapy with other antiretroviral agents to manage the viral load and prevent the progression to AIDS.
Key Ingredient
Key Benefits
- Videx helps in reducing the viral load (amount of HIV in the blood), which can lower the risk of transmitting HIV and help maintain better overall health.
- By reducing the HIV viral load, Videx helps increase CD4 cell counts, which are a measure of immune system health.
- Videx, when used as part of a combination therapy, helps slow the progression of HIV to AIDS.
- Videx is available in both tablet and powder forms, allowing flexibility in how it is administered.
Direction of Use
- The recommended dose for adults is usually one tablet daily, depending on the individual's response and physician's recommendations. For some patients, the dose may be divided into two doses daily.
- This form is typically used for children or individuals who cannot swallow tablets. The powder is mixed with water and taken once or twice a day.
- Videx can be taken on an empty stomach or with food, but it is important to follow your healthcare provider's instructions for optimal absorption.
- Patients on Videx should have their liver function and pancreatic enzymes monitored regularly, as Didanosine can cause liver toxicity and pancreatitis in some individuals.
Safety Concerns
- Videx can increase the risk of pancreatitis (inflammation of the pancreas), a potentially serious side effect. Symptoms include severe abdominal pain, nausea, and vomiting, and immediate medical attention is needed if these occur.
- Videx can cause liver problems, including elevated liver enzymes and liver failure, particularly in individuals with pre-existing liver conditions.
- Some patients may develop nerve damage (peripheral neuropathy), leading to symptoms like numbness, tingling, or pain in the hands and feet.
- Didanosine has been associated with lactic acidosis, a serious condition involving a buildup of lactic acid in the body, which can be fatal if untreated.
- Nausea, vomiting, and diarrhea are common side effects of Videx. These symptoms typically improve over time, but they should be monitored closely.
- Videx can interact with other medications, particularly those affecting liver enzymes. It’s important to inform your healthcare provider about any other medications you are taking.
Avoid Videx (Didanosine) If
- You are allergic to Didanosine or any of its ingredients.
- You have a history of pancreatitis or other pancreatic diseases.
- You have severe liver disease or hepatic failure.
- You are pregnant or planning to become pregnant (Didanosine is a Category C drug, meaning its effects on pregnancy are not fully understood, and it should only be used if absolutely necessary).
- You are breastfeeding, as Didanosine can pass into breast milk.
- You have a history of peripheral neuropathy or other nerve damage conditions.
- You have a history of lactic acidosis or any conditions that predispose you to metabolic issues.
