Arthrotec (Diclofenac / Misoprostol)

Arthrotec (Diclofenac / Misoprostol)

Arthrotec is a combination medication used primarily to manage symptoms & signs of: 

• Osteoarthritis 
• Rheumatoid arthritis, 
• Ankylosing spondylitis
• Acute musculoskeletal disorders

It combines two active ingredients: diclofenac, a nonsteroidal anti-inflammatory drug (NSAID), and misoprostol, a prostaglandin analog. 

Diclofenac helps reduce inflammation, pain, and fever, while misoprostol helps protect the stomach lining from the ulcerogenic effects of NSAIDs. 

Product Highlights

• Arthrotec combines the anti-inflammatory and analgesic properties of diclofenac with the gastric protective effects of misoprostol.
• Designed to reduce the risk of gastrointestinal ulcers and bleeding associated with long-term NSAID use.
• Typically available in tablet form, which simplifies administration.
• Diclofenac a potent NSAID that reduces inflammation, pain, and fever by inhibiting the production of prostaglandins (chemicals in the body that promote inflammation and pain).
• Misoprostol a synthetic prostaglandin E1 analog that protects the stomach lining by reducing acid secretion and increasing mucus production.

Key Ingredients

• Diclofenac Sodium 50 mg
• Misoprostol 200 mcg

Key Benefits

• Effective in reducing arthritis-related pain and inflammation.
• Helps prevent the development of ulcers and bleeding in the stomach and intestines, a common side effect of NSAIDs.
• Provides the benefits of an NSAID with reduced risk of gastrointestinal complications.

Direction For Use

• Follow your healthcare provider's instructions for dosage. Typically, it involves taking one tablet twice or three times daily, depending on your specific condition and response.
• Take the tablets with food or milk to minimize stomach upset. 
• Use as prescribed for the best results. Do not exceed the recommended dose.

Safety Concern

• Despite misoprostol’s protective effects, some patients might still experience gastrointestinal side effects.
• Long-term use of NSAIDs can affect kidney function; regular monitoring may be needed.
• NSAIDs, including diclofenac, can increase the risk of cardiovascular events, such as heart attack and stroke.

Avoid Arthrotec (Diclofenac / Misoprostol) If

• You are allergic to diclofenac, misoprostol, or any other ingredients in the medication.
• Misoprostol can cause uterine contractions and is not recommended during pregnancy, especially in the first and third trimesters.
• Avoid if you have certain gastrointestinal conditions (e.g., peptic ulcer disease), severe kidney or liver problems, or certain heart conditions.
• If you are taking medications that interact adversely with either diclofenac or misoprostol, consult your healthcare provider.