Information about Oruvail (Ketoprofen ER)
Oruvail is a brand name for an extended-release (ER) formulation of ketoprofen, a nonsteroidal anti-inflammatory drug (NSAID). It is typically used for the management of pain and inflammation associated with various musculoskeletal conditions and is designed to provide prolonged effects with less frequent dosing compared to immediate-release versions.
Product Highlights
- Oruvail (Ketoprofen ER) is typically prescribed for the treatment of:
- To manage chronic pain and inflammation in joints.
- To reduce inflammation and pain associated with this autoimmune condition.
- For the relief of pain resulting from soft tissue injuries like sprains and strains.
- Conditions involving inflammation and pain that can benefit from NSAIDs.
Key Ingredient
Key Benefits
- Reduces pain and inflammation, providing relief from conditions such as arthritis and muscle injuries.
- The ER formulation helps maintain a more consistent level of medication in the bloodstream, allowing for once-daily dosing.
- The extended-release nature of the tablet allows for less frequent dosing compared to immediate-release ketoprofen.
- Helps improve patient adherence to the medication regimen due to fewer doses per day.
Direction of Use
- Typically, Oruvail (Ketoprofen ER) is taken once a day, preferably with food to minimize gastrointestinal irritation.
- Swallow the tablet whole with a glass of water. Do not crush or chew the tablet, as this may alter the release mechanism and increase the risk of side effects.
- For certain conditions or in patients with kidney or liver impairment, dosage adjustments may be required, so always follow a healthcare provider's instructions.
Safety Concerns
- Like other NSAIDs, ketoprofen can cause gastrointestinal side effects, such as ulcers, bleeding, or perforation. The risk of these complications may rise with prolonged use.
- Long-term use of NSAIDs like ketoprofen has been associated with an increased risk of heart attack, stroke, and other cardiovascular events, especially at higher doses.
- Ketoprofen may impair kidney function, particularly in patients with pre-existing kidney issues, and should be used with caution in such individuals.
- There is potential for liver toxicity with prolonged use, so liver function tests should be monitored periodically during treatment.
- Rare but serious allergic reactions, including anaphylaxis, can occur with NSAIDs.
- Ketoprofen is generally contraindicated during the third trimester of pregnancy and should be used cautiously during the first and second trimesters. It is also passed into breast milk, so breastfeeding mothers should exercise caution.
Avoid Oruvail (Ketoprofen ER) If
- Patients with a known allergy to ketoprofen, aspirin, or other NSAIDs should avoid using Oruvail.
- Those with a history of gastrointestinal bleeding, peptic ulcers, or inflammatory bowel diseases (e.g., Crohn’s disease or ulcerative colitis) should not use this medication.
- Individuals with severe cardiovascular conditions, including heart failure or a history of heart attack or stroke, should avoid ketoprofen or use it under strict medical supervision.
- Patients with severe kidney or liver dysfunction should not take ketoprofen, as it can worsen renal or hepatic failure.
- Ketoprofen can cause fetal harm in the third trimester and should not be used during this period.
- Those with a history of NSAID-induced asthma, hives, or other allergic reactions should avoid ketoprofen.
