Information about Periactin (Cyproheptadine)
Periactin is a brand name for cyproheptadine, an antihistamine with additional properties as an appetite stimulant. It is commonly used to treat allergic reactions such as hay fever, hives, and other allergy-related symptoms. Cyproheptadine works by blocking histamine and serotonin receptors, which helps to reduce allergic responses and may also promote weight gain by stimulating appetite. It is available in tablet and syrup forms, and it is sometimes prescribed for off-label uses such as the treatment of migraines or to increase appetite in individuals who have difficulty gaining weight.
Product Highlights
- Cyproheptadine is commonly used to treat allergy-related symptoms such as sneezing, runny nose, itching, and watery eyes caused by conditions like hay fever (allergic rhinitis).
- It is also used to relieve symptoms of urticaria, which includes skin rashes, itching, and hives.
- In some cases, cyproheptadine is used as an appetite stimulant for people who have difficulty gaining weight, particularly in children, patients with eating disorders, or those suffering from conditions such as cancer or HIV.
- Although not FDA-approved for this use, cyproheptadine is sometimes prescribed off-label for the prevention of migraines, as it can help with the vasoconstriction of blood vessels.
- It may be used in certain cases to help manage serotonin syndrome, a potentially life-threatening condition caused by excess serotonin in the brain.
Key Ingredient
Key Benefits
- Effective for the relief of hay fever, allergic rhinitis, and urticaria by reducing histamine-related symptoms such as itching, sneezing, and watery eyes.
- Cyproheptadine is often used to increase appetite in individuals who are underweight or struggling to gain weight, particularly those recovering from illness or with certain medical conditions.
- While not a primary indication, cyproheptadine is sometimes used to prevent migraines or reduce their severity.
- Due to its sedating effects, cyproheptadine can also be helpful for individuals who need assistance with sleep or calming anxiety, though this side effect can also be a drawback.
Direction of Use
- The typical starting dose for adults is 4 mg (one tablet) two or three times a day. For children, the dosage is determined according to their age and weight.
- Take the tablet or syrup as instructed, with or without food. For the syrup form, use the provided measuring device for accurate dosing.
- The dose may be slowly increased based on response and tolerance, with the usual maximum dose for adults being 12 mg per day.
- If you miss a dose, take it as soon as you remember. If it's nearly time for your next dose, skip the missed dose. Do not take two doses at once to make up for the missed dose.
- It is important to follow the healthcare provider's recommendations for long-term use, especially for appetite stimulation, to avoid possible side effects.
Safety Concerns
- Cyproheptadine can cause drowsiness and should be used cautiously when driving or operating machinery.
- Combining cyproheptadine with alcohol, sedatives, or other central nervous system depressants can increase sedative effects, leading to excessive drowsiness or impaired coordination.
- May cause dry mouth, blurred vision, urinary retention, and constipation, especially in older adults.
- When used for appetite stimulation, cyproheptadine may lead to weight gain, which can be undesirable for some individuals.
- The safety of cyproheptadine in children under 2 years old has not been established, and it should be used with caution in young children.
Avoid Periactin (Cyproheptadine) If
- Avoid use if you are allergic to cyproheptadine or any other antihistamines.
- Cyproheptadine may increase intraocular pressure and should be avoided in individuals with narrow-angle glaucoma.
- People with severe liver or kidney conditions should avoid using cyproheptadine, as it may exacerbate these conditions.
- Cyproheptadine is excreted in breast milk and should be avoided during breastfeeding unless advised by a healthcare provider.
- Not recommended for use in children under 2 years of age.
- Avoid combining cyproheptadine with alcohol, sleeping pills, or other sedating medications without medical supervision, as this can lead to excessive sedation.
