Information about Rocaltrol (Calcitriol)
Rocaltrol (generic name: Calcitriol) is the active form of vitamin D3, which is used to regulate calcium and phosphate levels in the body. It works by promoting calcium absorption in the intestines, increasing calcium reabsorption in the kidneys, and stimulating the release of calcium from bones into the bloodstream. Rocaltrol is primarily used in conditions where calcium regulation is disrupted, such as in chronic kidney disease or certain types of bone disorders.
Product Highlights
- In patients with kidney failure or impaired kidney function, Rocaltrol helps manage low calcium levels and phosphate imbalances.
- Often seen in patients with kidney disease or certain parathyroid disorders, calcitriol helps raise calcium levels in the blood.
- Particularly in patients with chronic kidney disease, Rocaltrol helps reduce excessive parathyroid hormone (PTH) levels.
- Used to support bone health and prevent fractures by improving calcium balance.
- Conditions caused by vitamin D deficiency, leading to weakened bones, where Rocaltrol helps correct calcium and phosphate imbalances.
- Can be used to increase calcium absorption in women post-menopause to reduce bone loss.
Key Ingredient
Key Benefits
- Helps to balance calcium and phosphate levels in the body, promoting healthy bones and preventing complications related to abnormal mineral levels.
- Rocaltrol is particularly beneficial for patients with bone disorders, like osteoporosis or osteomalacia, as it enhances calcium absorption to maintain strong bones.
- By modulating calcium and phosphate levels, Rocaltrol can help manage hyperparathyroidism, commonly seen in kidney disease patients.
- For patients with chronic kidney disease, it helps prevent the progression of bone disease and mineral imbalances by restoring calcium and phosphate balance.
Direction of Use
- Rocaltrol is typically taken orally as capsules or liquid form. The dosage varies depending on the condition being treated and the patient's individual needs.
- For chronic kidney disease or hypocalcemia, the initial dose may start at 0.25 mcg to 1 mcg per day, adjusting as needed.
- For osteoporosis or postmenopausal conditions, it may be given as a lower dose, based on the patient’s calcium levels and response.
- Rocaltrol can also be administered as an intravenous injection in certain medical settings, such as in dialysis patients with severe calcium imbalances.
Safety Concerns
- Overuse of Rocaltrol or high doses can lead to elevated calcium levels in the blood (hypercalcemia), causing symptoms like nausea, vomiting, confusion, or kidney problems.
- As Rocaltrol affects calcium metabolism, patients with pre-existing kidney issues need careful monitoring for signs of kidney damage or worsened kidney function.
- In patients with kidney disease, too much calcium can bind with phosphate and lead to calcification of tissues.
- Excessive use can lead to weakened bones or pain, especially if calcium levels get too high.
- Certain medications, like thiazide diuretics, may increase the risk of hypercalcemia when combined with Rocaltrol.
Avoid Rocaltrol (Calcitriol) If
- Rocaltrol should not be used if you have high calcium levels (hypercalcemia) or calcium in your urine (hypercalciuria), as it may worsen these conditions.
- Patients with severe kidney impairment should avoid Rocaltrol or use it only under strict medical supervision, as the medication can worsen kidney function.
- If you have vitamin D toxicity, avoid Rocaltrol since it could further increase calcium levels in the body.
- If you are allergic to calcitriol or any of the excipients in the formulation, you should not use Rocaltrol.
- Rocaltrol should only be used during pregnancy if absolutely necessary, as it may harm the fetus. It is unknown whether calcitriol passes into breast milk, so breastfeeding mothers should consult their healthcare provider before using it.
