Reclast (Zolendronic acid)

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Brand Name : Reclast

Marketing Authorization Holder : Novartis

Prescription Required

 
 

Generic Option

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Generic Name : Zolendronic acid

Manufactured By : Authorized UK Generic

Prescription Required

 
 

Product Details

Reclast

In the Europe, Reclast is called Aclasta. Both medicines are made by Novartis and contain zolendronic acid 5mg per 100ml. Reclast is also available in a generic equivalent in the United Kingdom offering additional savings.

Prescription Reclast is used in the treatment of osteoporosis and other conditions where the bones become thin. Reclast is given as an infusion that last 15 minutes. Although you may eat normally before the infusion, one hour before the infusion you should drink 2 glasses of fluid. Reclast is usually infused once per year or every two years. Infusion of Reclast is administered by a healthcare provider.

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Information about Reclast (Zolendronic Acid)

Reclast is a medication that contains zolendronic acid, a type of bisphosphonate used primarily to treat bone-related conditions. Zolendronic acid works by inhibiting the activity of osteoclasts, the cells responsible for bone breakdown, which helps increase bone density and strength. Reclast is typically administered intravenously (IV) by a healthcare provider and is used for conditions such as osteoporosis, Paget's disease of bone, and to prevent fractures in patients with certain cancers.

Product Highlights

  • Reclast is used to treat osteoporosis in postmenopausal women, men with osteoporosis, and people on long-term corticosteroid therapy to reduce the risk of fractures.
  • This medication is also used to treat Paget's disease, a condition where the bone becomes fragile due to abnormal bone remodeling.
  • Reclast is used to treat or prevent bone complications associated with cancer, such as bone fractures and hypercalcemia (high calcium levels in the blood) caused by cancer.

Key Ingredient

  • Zolendronic Acid

Key Benefits

  • Reclast helps increase bone mass and strength, reducing the risk of fractures in people with osteoporosis.
  • In patients with osteoporosis, it significantly lowers the chances of fractures, especially in the spine, hip, and other bones.
  • Reclast alleviates bone pain and enhances the structure of bones affected by Paget's disease. 
  • Reclast is administered as an intravenous infusion, typically once a year for osteoporosis, making it a convenient alternative to daily or weekly oral medications.
  • It can reduce the risk of bone fractures and other complications in patients with cancer-related bone issues.

Direction of Use

  • Reclast is administered through an intravenous infusion by a healthcare professional. For osteoporosis, it is typically administered once a year, while for Paget’s disease or cancer-related bone complications, it may be given more frequently based on the patient’s condition.
  • The infusion usually lasts for about 15 minutes. Patients may be observed for side effects during and after the infusion. 
  • Patients are often advised to drink plenty of fluids before receiving Reclast to help prevent kidney problems.
  • Regular follow-up visits and blood tests are necessary to check calcium levels and kidney function.

Safety Concerns

  • Reclast can cause kidney issues, so kidney function should be monitored before and during treatment. It is important to ensure that the patient is adequately hydrated before receiving the infusion.
  • Reclast may increase the risk of osteonecrosis of the jaw, a condition where the jawbone begins to weaken and die, especially after dental procedures.
  • Zolendronic acid may lower calcium levels in the blood, leading to hypocalcemia (low blood calcium). Calcium levels should be checked before administration, and patients may be given calcium supplements if necessary.
  • Some individuals may experience flu-like symptoms, including fever, muscle aches, or chills, after receiving the infusion. 
  • Long-term use of bisphosphonates like Reclast may increase the risk of rare types of fractures in the thigh bone (femur).
  • Reclast should not be used during pregnancy or breastfeeding, as it can harm the fetus or infant.

Avoid Reclast (Zolendronic Acid) If

  • You have an allergy to zolendronic acid or any of the ingredients in Reclast. 
  • You have severe kidney problems or a creatinine clearance of less than 35 mL/min.
  • You are pregnant or planning to become pregnant.
  • You are breastfeeding.
  • You have hypocalcemia (low calcium levels in the blood) that has not been corrected.
  • You have a history of osteonecrosis of the jaw or other bone-related issues.
  • You have a history of esophageal disease, as Reclast can irritate the esophagus.
  • You have or have had low blood calcium levels or other mineral imbalances that have not been treated.


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