Sanctura is called Regurin in Europe.
Information about Sanctura (Trospium)
Sanctura, containing the active ingredient trospium, is a medication used to treat overactive bladder (OAB) symptoms, including urinary frequency, urgency, and incontinence. Trospium is an antimuscarinic agent that works by blocking the action of acetylcholine, a neurotransmitter involved in bladder muscle contractions. This helps reduce bladder spasms and provides relief from the symptoms of OAB.
Product Highlights
- Sanctura is used to manage the symptoms of overactive bladder (OAB), such as frequent urination, urgency, and incontinence.
- It may also be prescribed for other bladder conditions related to involuntary muscle contractions.
Key Ingredient
Key Benefits
- Sanctura effectively reduces symptoms of OAB, including frequent urination, urgency, and leakage, improving patients' quality of life.
- By reducing bladder muscle spasms, it allows for better control over urination, reducing the sudden and uncontrollable urge to urinate.
- The extended-release form of Sanctura offers once-daily dosing, which can improve adherence and convenience for patients.
Direction of Use
- The usual dosage for adults is typically 60 mg once daily, but it may be adjusted based on the patient's response and tolerance.
- Sanctura should be taken on an empty stomach, at least one hour before meals, to enhance absorption.
- The extended-release tablet should be swallowed whole and not crushed, broken, or chewed, as this may affect its effectiveness.
- Taking Sanctura at the same time every day is important to ensure consistent blood levels and effective symptom control.
Safety Concerns
- A common side effect of Sanctura is dry mouth, which occurs due to the reduction in glandular secretions caused by trospium.
- Some patients may experience constipation or difficulty emptying the bladder.
- Trospium can affect the eyes and cause blurred vision or dizziness, especially when standing up quickly.
- There may be cognitive side effects, particularly in older adults, such as confusion, memory problems, or difficulty concentrating.
- Caution should be exercised in patients with heart conditions, as antimuscarinic drugs can increase heart rate or cause other cardiovascular side effects.
- Older adults are more sensitive to the side effects of Sanctura, such as confusion, blurred vision, and constipation.
Avoid Sanctura (Trospium) If
- Sanctura should not be used in individuals with angle-closure glaucoma or uncontrolled narrow-angle glaucoma due to the potential for increased intraocular pressure.
- Patients with urinary retention, bladder outlet obstruction, or severe constipation should avoid Sanctura, as it can worsen these conditions.
- Individuals with a known allergy to trospium or any of the excipients in the formulation should not take Sanctura.
- Caution is advised for patients with significant kidney or liver impairment, as these conditions can affect the metabolism and excretion of the drug.
- Sanctura is generally not recommended during pregnancy and breastfeeding unless clearly needed, as its safety in these situations has not been well studied.
