Sanctura XL (Trospium ER)

Sanctura XL is called Regurin XL in Europe.

Information about Sanctura XL (Trospium ER)

Sanctura XL (Trospium ER) is an extended-release formulation of trospium, an antimuscarinic medication used to treat overactive bladder (OAB) symptoms. Trospium works by inhibiting the action of acetylcholine on the bladder, reducing involuntary contractions that lead to frequent urination, urgency, and incontinence. Sanctura XL provides continuous, sustained relief from these symptoms, improving bladder control for patients with OAB.

Product Highlights

• Sanctura XL is used to treat symptoms of OAB, including frequent urination, urgency, and incontinence, in adults.
• It is particularly effective in managing bladder spasms and improving urinary control in patients suffering from these conditions.

Key Ingredient

• Trospium

Key Benefits

• Sanctura XL effectively reduces symptoms such as urinary frequency, urgency, and incontinence, improving the quality of life for individuals with OAB.
• The extended-release formulation allows for once-daily dosing, improving patient adherence to the treatment regimen.
• The extended-release nature of Sanctura XL reduces the potential for side effects like dry mouth and constipation, which are common with immediate-release forms of antimuscarinics.
• Unlike some other medications for OAB, Sanctura XL is less likely to cause sedation or interfere with daily activities.

Direction of Use

• The typical dose of Sanctura XL is 60 mg once daily. Your healthcare provider may modify the dosage according to your specific needs. 
• Sanctura XL should be taken on an empty stomach, at least one hour before meals, to maximize absorption.
• It is important to take Sanctura XL at the same time each day to maintain steady blood levels and achieve optimal symptom control.
• The extended-release tablet should be swallowed whole and should not be broken, chewed, or crushed, as this may interfere with the controlled release of the medication.

Safety Concerns

• As with other antimuscarinic medications, Sanctura XL can cause dry mouth, which may lead to discomfort.
• Some patients may experience constipation as a side effect due to the medication’s action on the digestive system.
• Trospium can cause blurred vision, dizziness, or lightheadedness, especially when standing up quickly.
• Older adults are particularly sensitive to the cognitive side effects of trospium, which may include confusion, memory problems, or difficulty concentrating.
• Caution is needed in patients with heart conditions, as antimuscarinic drugs like Sanctura XL may cause increased heart rate or other cardiovascular side effects.
• Patients with kidney or liver disease may need adjustments to the dose of Sanctura XL, as the drug is metabolized by the liver and excreted through the kidneys.

Avoid Sanctura XL (Trospium ER) If

• Sanctura XL should be avoided by individuals with narrow-angle glaucoma or uncontrolled open-angle glaucoma, as it can increase intraocular pressure.
• Patients with urinary retention, bladder outlet obstruction, or severe constipation should not take Sanctura XL, as it may exacerbate these conditions.
• Individuals who are allergic to trospium or any of the components of the formulation should avoid using Sanctura XL.
• Caution is required in patients with severe kidney or liver impairment, and Sanctura XL may be contraindicated in these individuals.
• The safety of Sanctura XL during pregnancy and breastfeeding has not been well established. It should be used during pregnancy only if the potential benefits outweigh the risks, and it is not recommended during breastfeeding.