Divigel is called Sandrena in Europe.
Information about Divigel (Estradiol)
Divigel is a transdermal gel formulation containing estradiol, a form of estrogen, which is used primarily in hormone replacement therapy (HRT). It helps alleviate symptoms associated with menopause and other estrogen deficiencies.
Product Highlights
- Management of moderate to severe vasomotor symptoms (e.g., hot flashes) due to menopause.
- Management of vulvar and vaginal atrophy related to menopause.
- Prevention of osteoporosis in postmenopausal women at high risk for fractures.
Key Ingredient
Key Benefits
- Effectively reduces hot flashes, night sweats, and vaginal dryness.
- Supports bone density, lowering the risk of osteoporosis.
- Can enhance overall well-being and comfort in menopausal women.
Direction of Use
- Apply a thin layer of Divigel to clean, dry, unbroken skin on the upper arm or thigh.
- Use the gel once daily, at the same time each day, as directed by a healthcare provider.
- Allow the gel to dry before dressing.
Safety Concerns
- Elevated risk of thromboembolic events (e.g., deep vein thrombosis, pulmonary embolism).
- Potentially elevated risk of breast or endometrial cancer.
- Caution is advised for women with a history of heart disease or stroke.
Avoid Divigel (Estradiol) If
- You have a known allergy to estradiol or any of the gel’s ingredients.
- You have a history of hormone-sensitive cancers (such as breast or uterine cancer).
- You have active or past thromboembolic disorders (e.g., DVT, PE).
- You have undiagnosed abnormal genital bleeding.
- You are pregnant or breastfeeding.
