Vivelle Dot is called Estradot in Europe. It is a twice weekly patch.
Information about Vivelle Dot (Estradiol)
Vivelle Dot is a transdermal patch that delivers estradiol, a form of estrogen, through the skin into the bloodstream. It is primarily used in hormone replacement therapy (HRT) for women experiencing symptoms related to menopause, such as hot flashes, night sweats, and vaginal dryness. The patch also helps prevent osteoporosis in postmenopausal women. Estradiol is the most potent form of estrogen and plays a crucial role in maintaining various bodily functions, including reproductive health.
Product Highlights
- Vivelle Dot is primarily prescribed to treat symptoms associated with menopause, including hot flashes, night sweats, and vaginal dryness.
- It is used to prevent osteoporosis in postmenopausal women, as estradiol helps maintain bone density.
- Vivelle Dot may be used to treat conditions that cause low estrogen levels, such as hypogonadism or oophorectomy (surgical removal of the ovaries).
Key Ingredient
Key Benefits
- Vivelle Dot helps relieve the common symptoms of menopause, such as hot flashes, mood swings, and vaginal dryness, which can significantly improve a woman's quality of life during this transition.
- By increasing estrogen levels, Vivelle Dot helps prevent bone loss and reduces the risk of osteoporosis in postmenopausal women.
- The transdermal patch provides a consistent release of estradiol over time, offering stable hormone levels and avoiding the fluctuations seen with oral medications.
- Since the patch is applied to the skin, it bypasses the digestive system, reducing potential gastrointestinal side effects and providing a more efficient method of absorption.
- The patch is typically worn for 3-4 days, providing a long-lasting and convenient option compared to daily oral medications.
Direction of Use
- Apply the Vivelle Dot patch to a clean, dry, and hairless area of the skin, such as the lower abdomen, buttocks, or upper thigh. It should be applied to a different site with each new patch to avoid skin irritation.
- The patch should be replaced twice a week, typically every 3 to 4 days, depending on the prescribed dose. The patch should be worn continuously for the entire period before being replaced.
- Avoid placing the patch on areas of the skin that are oily, irritated, or damaged. Do not apply the patch to your breasts.
- After removing the patch, fold it in half with the sticky sides together and discard it safely, out of the reach of children and pets.
Safety Concerns
- Estradiol can increase the risk of blood clots, which can lead to conditions like deep vein thrombosis (DVT), pulmonary embolism (PE), or stroke. Patients with a history of blood clots should be monitored closely.
- Long-term use of estrogen, especially without progesterone, has been associated with an increased risk of endometrial cancer and possibly breast cancer. Regular check-ups are important to monitor for these risks.
- Estradiol may increase the risk of heart disease and stroke in women with certain risk factors, such as hypertension, smoking, or a history of cardiovascular disease.
- Some women may experience gallbladder disease while using estrogen therapy, including Vivelle Dot.
- Liver function should be monitored during treatment, as estrogen can affect liver enzyme levels.
- Some side effects of Vivelle Dot include nausea, headaches, mood changes, breast tenderness, and skin reactions at the patch site.
Avoid Vivelle Dot (Estradiol) If
- Do not use Vivelle Dot if you have a history of hormone-sensitive cancers, such as breast, ovarian, or uterine cancer.
- Avoid Vivelle Dot if you have a history of blood clots, deep vein thrombosis (DVT), pulmonary embolism (PE), or stroke.
- Women with active liver disease or liver tumors should not use Vivelle Dot, as the medication may worsen liver conditions.
- If you experience unexplained vaginal bleeding, consult your healthcare provider before starting Vivelle Dot.
- Vivelle Dot should not be used during pregnancy, as estradiol can harm the developing fetus. It is also contraindicated during breastfeeding, as estradiol can be excreted in breast milk.
- If you are allergic to estradiol or any of the components of Vivelle Dot, it should not be used.
