Ocaliva (Obeticholic acid)

Prescription Ocaliva is a treatment for primary biliary cholangitis (PBC), usually alongside of ursodeoxycholic acid (ursodiol). Ocaliva is used by adults who have not responded to ursodeoxycholic acid (ursodiol) alone or who cannot tolerate it.

Ocaliva may lower ALP (alkaline phosphatase) levels which are often caused by liver disease. High ALP levels are a key marker used to track PBC and measuring the effectiveness of treatment. Ocaliva may show a reduction in ALP levels after 2 weeks of treatment. Ongoing studies are being conducted to find out if Ocaliva patients live longer or if their symptoms improve after treatment.

Ocaliva should be taken exactly as prescribed with or without food.

Ocaliva reduces toxic bile build up caused by PBC which damages the liver. Ocaliva increases the flow of bile acids and reduces production of bile acids.

Ocaliva requires simple regular testing for ALP every 3 to 6 months to measure the changes produced by treatment.

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