Prescription Toctino contains the active ingredient alitretinoin. Toctino is available in Canada and Europe for the treatment of adults with severe chronic hand eczema which has not responded to other treatments. Alitretinoin is classified as a retinoid,a chemical related to vitamin A.
Toctino must be prescribed by a dermatologist who is treating a patient who has started treatment with Toctino by a physician in a country where Toctino is approved OR when the US physician has explored all other options and has deemed Toctino as medically necessary for import.
Women prescribed Toctino must first be tested for pregnancy. If there is a chance of becoming pregnant, do not take Toctino because Toctino can cause serious damage to an unborn child. Female patients taking Toctino are prescribed birth control before starting Toctino and must continue for 1 month after taking Toctino.
Patients taking Toctino soft gel capsules will take one capsules daily with the main meal of the day. The Toctino capsules are swallowed at dose of either 10mg or 30mg daily. The 10mg Toctino dose is usually recommended if 30mg cannot be tolerated. The duration of Toctino treatment is usually 12 to 24 weeks depending on the condition and how well you respond to the medicine. If Toctino is successful, your physician may again prescribe another course if symptoms return some time later.
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Information about Toctino (Alitretinoin)
Toctino is a prescription medication that contains alitretinoin, a synthetic retinoid used primarily for the treatment of severe chronic hand eczema (also known as chronic hand dermatitis) that has not responded to other treatments. Alitretinoin is related to vitamin A and works by influencing the activity of skin cells to help reduce inflammation and improve skin condition.
Product Highlights
- Toctino is specifically indicated for the treatment of severe chronic hand eczema, especially in cases that have not improved with topical therapies or corticosteroids.
- It is used to reduce the severity of skin lesions caused by the condition and improve the quality of life for patients with debilitating symptoms of hand eczema.
Key Ingredient
Key Benefits
- Toctino is particularly beneficial for patients with severe chronic hand eczema that has not responded to topical treatments or corticosteroids.
- Alitretinoin helps to reduce redness, scaling, and thickening of the skin caused by eczema, leading to significant improvement in the appearance and texture of the skin.
- By alleviating the discomfort and symptoms associated with chronic hand eczema (such as pain, cracking, and itching), Toctino can significantly enhance the quality of life for affected patients.
- As an oral medication, Toctino provides a more comprehensive treatment approach compared to topical options, particularly in severe or widespread cases.
Direction of Use
- The typical recommended dose of Toctino is 10 mg or 30 mg per day, depending on the severity of the condition and the patient’s response to the medication. It is important to follow the specific dosage prescribed by your healthcare provider.
- Toctino is taken orally with food, usually once a day. The capsules should be swallowed whole with water.
- Treatment usually lasts for up to 12 to 24 weeks, depending on the patient's progress and response to the medication.
- It is important to take the medication consistently as prescribed and not to discontinue it prematurely, even if you start to see improvement.
- Regular follow-up appointments with your healthcare provider are necessary to monitor progress, side effects, and adjust dosing if needed.
Safety Concerns
- Alitretinoin can cause serious birth defects and should not be used during pregnancy. Women of childbearing age must use effective contraception during treatment and for at least one month after discontinuation of Toctino. Pregnancy tests should be done before starting treatment and during treatment to ensure the patient is not pregnant.
- Alitretinoin can affect liver function, so liver enzymes should be monitored regularly during treatment. Any signs of liver problems, such as jaundice or dark urine, should be reported immediately.
- Retinoids, including alitretinoin, have been associated with mood changes, depression, and anxiety in some patients. It’s important to monitor for any psychological symptoms and seek support if necessary.
- Dryness of the skin, lips, and eyes is a common side effect of Toctino. It is important to hydrate the skin regularly and use moisturizing creams or lip balms as needed.
- Alitretinoin can increase skin sensitivity to the sun, so sun protection measures should be taken, such as wearing sunscreen and avoiding excessive sun exposure.
Avoid Toctino (Alitretinoin) If
- You are pregnant or planning to become pregnant, as Toctino can cause severe birth defects.
- You are breastfeeding, as alitretinoin may pass into breast milk and harm the baby.
- You have a history of severe liver disease, as Toctino may worsen liver function.
- You are allergic to alitretinoin or any of the other ingredients in the medication.
- You are taking other retinoids or medications that affect liver function, as these can increase the risk of adverse effects.
- You have severe dry eye or other vision problems, as alitretinoin may exacerbate these conditions.
- You are planning to undergo skin laser treatments or have significant sun exposure, as the skin may become more sensitive.
