Oracea (Doxycyline DR)

Oracea is called Efracea in Europe.

Information about Oracea (Doxycycline DR)

Oracea is a delayed-release formulation of doxycycline, an antibiotic belonging to the class of tetracyclines. It is primarily used for the treatment of rosacea, a chronic skin condition that causes redness, pimples, and visible blood vessels, typically on the face. Oracea helps reduce inflammation and the number of lesions associated with rosacea, and it may also provide some antimicrobial effects. Unlike other forms of doxycycline, Oracea's delayed-release formulation is designed to minimize the risk of gastrointestinal side effects and improve patient compliance.

Product Highlights

• Oracea is primarily indicated for the management of moderate to severe inflammatory rosacea. It helps reduce the redness, inflammation, and lesions associated with this chronic skin condition. It is especially useful for the papulopustular type of rosacea (pimples and pustules).
• Oracea is used for its anti-inflammatory effects in rosacea and is not typically used to treat the infection aspect of the condition.

Key Ingredient

• Doxycycline

Key Benefits

• Oracea helps to control the inflammatory symptoms of rosacea, including facial redness, swelling, and pustules. This leads to an overall improvement in skin appearance and quality of life.
• The once-daily dosage improves convenience and adherence to treatment, making it easier for patients to integrate into their daily routine.
• The delayed-release formulation of Oracea reduces the likelihood of gastrointestinal side effects commonly associated with doxycycline and other tetracyclines, such as nausea, stomach upset, and irritation.
• Oracea helps with the long-term management of rosacea symptoms, potentially reducing flare-ups and the need for stronger treatments.

Direction of Use

• The recommended dose of Oracea is typically 40 mg once daily, taken in the morning on an empty stomach (at least 1 hour before or 2 hours after a meal).
• Swallow the capsule whole with a full glass of water. Do not crush, chew, or break the capsule to ensure proper release of the medication.
• It is important to take Oracea at the same time every day to help establish a routine and ensure consistent therapeutic effects.
• It is recommended to remain upright for at least 30 minutes after taking Oracea to reduce the risk of irritation to the esophagus and stomach.

Safety Concerns

• Although Oracea is formulated to minimize stomach upset, doxycycline may still cause esophageal irritation, nausea, or vomiting in some individuals. To minimize the risk, it’s important to take the capsule with a full glass of water and remain upright for at least 30 minutes after taking the medication.
• Like other tetracyclines, doxycycline may increase sensitivity to sunlight, making patients more prone to sunburn. It is important to avoid prolonged sun exposure and to wear protective clothing or sunscreen.
• Oracea should be avoided during pregnancy unless absolutely necessary, as tetracyclines can affect the development of the baby’s bones and teeth. It is also advised to avoid breastfeeding while using this medication.
• Doxycycline can interact with other medications, including antacids, calcium supplements, iron supplements, and certain antibiotics, which may reduce its effectiveness. It’s essential to inform your healthcare provider about all the medications you are currently taking.
• Patients with liver or kidney problems should use Oracea with caution. Dosage adjustments may be necessary for patients with significant organ impairment.
• Rarely, some people may have an allergic reaction to doxycycline, which may include rash, swelling, or difficulty breathing. If you develop these symptoms, contact a healthcare professional without delay.

Avoid Oracea (Doxycycline DR) If

• You are allergic to doxycycline or any other tetracycline antibiotics (e.g., tetracycline, minocycline).
• You are pregnant or planning to become pregnant, as doxycycline can affect the development of bones and teeth in a developing fetus.
• You are breastfeeding, as doxycycline can pass into breast milk and may harm a nursing infant.
• You have severe liver disease or impaired liver function, as doxycycline is metabolized by the liver.
• You have severe kidney disease, as adjustments to the dosing may be required.
• You have esophageal problems or difficulty swallowing, as there is an increased risk of irritation or ulceration of the esophagus when taking doxycycline.