Ferriprox (Deferiprone)

Prescription Ferriprox contains deferiprone, an iron chelator which removes excess amounts of iron from the body. Ferriprox is a treatment of iron overload caused by blood transfusions in thalassaemia major when there is inadequate response to current chelation therapy or it is contraindicated. The safety of Ferriprox as an iron chelator in other types of long lasting anemia has not been established.

Ferriprox should be taken exactly as directed by your physician. Ferriprox dose is based on the weight of the patient. A standard dose for an adult is 25mg/kg three times per day which often means 2000mg three times per day. The total daily dose of Ferriprox should not exceed 100mg/kg. 

Ferriprox can be taken with or without food, usually in morning, midday and evening. Aluminum based antacids are not taken at the same time as Ferriprox.

If you forget a dose of Ferriprox, take as soon as you remember and take your next dose at the regular time. Never double your dose of Ferriprox. Never change your Ferriprox dose without speaking with your physician.

Before beginning Ferriprox and during the first week of therapy, your physician will give you a neutrophil count test. Your doctor may check your blood levels regularly depending on your white blood cell count. Low white blood cell count is not uncommon and can be a serious side effect of Ferriprox. Serious infections can occur if your neutrophil count (one type of white blood cell) gets too low. Severe neutropenia is called agranulocytosis which can become life threatening.

If you get any symptoms of infection like fever, sore throat, mouth stores, chills or flu like symptoms, stop taking Ferriprox immediately and contact your physician.

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Information about Ferriprox (Deferiprone)

Ferriprox is an iron chelator used primarily to treat iron overload in patients with thalassemia and other chronic anemias who require frequent blood transfusions. It works by binding excess iron in the body, facilitating its excretion.

Product Highlights

• Treatment of chronic iron overload due to repeated blood transfusions in patients with thalassemia or other chronic anemias.
• May be used in other conditions leading to iron overload, as directed by a healthcare provider.
• Binds free iron, reducing iron stores and preventing organ damage.

Key Ingredient

• Deferiprone

Key Benefits

• Proven efficacy in reducing serum ferritin levels and iron burden.
• Helps prevent complications related to iron overload, such as heart and liver damage.
• Oral administration allows for ease of use compared to some intravenous iron chelators.

Direction of Use

• Take Ferriprox exactly as prescribed by your healthcare provider. 
• It can be taken with or without food, but consistency is key to maintaining effective levels in the body.

Dosage Table

To obtain a dose of about 75 mg/kg/day, use the dose suggested in the following table for the body weight of the patient.

Dosage table for Ferriprox 1000 mg tablets

Safety Concerns

• Nausea, vomiting, abdominal pain, and diarrhea.
• Risk of agranulocytosis (a severe drop in white blood cell count); regular blood monitoring is essential.
• Potential interactions with other medications; consult your healthcare provider if you are taking additional treatments.

Avoid Ferriprox (Deferiprone) If

• You have a known hypersensitivity to deferiprone or any of its components.
• You have a history of agranulocytosis or other blood disorders.
• You are pregnant or nursing without first consulting a healthcare provider.
• You are currently taking medications that may increase the risk of bone marrow suppression.