Ferriprox (Deferiprone)

Prescription Ferriprox contains deferiprone, an iron chelator which removes excess amounts of iron from the body. Ferriprox is a treatment of iron overload caused by blood transfusions in thalassaemia major when there is inadequate response to current chelation therapy or it is contraindicated. The safety of Ferriprox as an iron chelator in other types of long lasting anemia has not been established.

Ferriprox should be taken exactly as directed by your physician. Ferriprox dose is based on the weight of the patient. A standard dose for an adult is 25mg/kg three times per day which often means 2000mg three times per day. The total daily dose of Ferriprox should not exceed 100mg/kg. 

Ferriprox can be taken with or without food, usually in morning, midday and evening. Aluminum based antacids are not taken at the same time as Ferriprox.

If you forget a dose of Ferriprox, take as soon as you remember and take your next dose at the regular time. Never double your dose of Ferriprox. Never change your Ferriprox dose without speaking with your physician.

Before beginning Ferriprox and during the first week of therapy, your physician will give you a neutrophil count test. Your doctor may check your blood levels regularly depending on your white blood cell count. Low white blood cell count is not uncommon and can be a serious side effect of Ferriprox. Serious infections can occur if your neutrophil count (one type of white blood cell) gets too low. Severe neutropenia is called agranulocytosis which can become life threatening.

If you get any symptoms of infection like fever, sore throat, mouth stores, chills or flu like symptoms, stop taking Ferriprox immediately and contact your physician.

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