Sporanox (Itraconazole)

Brand Options

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Brand Name : Sporanox

Marketing Authorization Holder : Janssen-Cilag

Prescription Required

 
 

Generic Option

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Generic Name : Itraconazole

Manufactured By : Authorized UK Generic

Prescription Required

 
 

Product Details

Sporanox

Information about Sporanox (Itraconazole)

Sporanox (Itraconazole) is an antifungal medication used to treat a range of fungal infections. It is effective against a broad spectrum of fungi and is commonly prescribed for conditions like blastomycosis, histoplasmosis, aspergillosis, and certain dermatophyte infections. Sporanox works by inhibiting the growth of fungi, preventing their reproduction, and helping the body eliminate the infection.

Product Highlights

  • Used for the treatment of invasive aspergillosis, a fungal infection that can affect the lungs and other organs.
  • A systemic fungal infection that primarily affects the lungs, skin, and bones.
  • An infection caused by the Histoplasma fungus, often affecting the lungs, and sometimes spreading to other organs.
  • Used to treat fungal infections of the skin, hair, and nails, such as ringworm and onychomycosis.
  • Can be used to treat other fungal infections as determined by a healthcare provider.

Key Ingredient

  • Itraconazole

Key Benefits

  • Itraconazole is effective against a wide range of fungi, including both systemic and superficial fungal infections.
  • Sporanox is available in oral capsule and liquid forms, making it convenient for patients to take.
  • It specifically targets fungal cells, minimizing damage to human cells.
  • Itraconazole is especially effective for the long-term treatment of systemic fungal infections. 
  • By treating infections effectively, it reduces symptoms such as pain, skin lesions, and respiratory issues associated with fungal infections.

Direction of Use

  • The usual adult dosage for most fungal infections is 200 mg to 400 mg daily, divided into one or two doses. For dermatophyte infections (like nail infections), it may be prescribed for several months depending on the severity and location of the infection.
  • The dosage for the oral solution may differ depending on the type of infection being treated and is typically prescribed by weight or condition. It is important to follow the healthcare provider's instructions for this formulation.
  • Capsules can be taken with or without food. However, the oral solution should be taken with food for better absorption.
  • If you miss a dose, take it as soon as you remember, unless it's close to the time for your next dose. Do not take two doses at the same time to compensate for a missed dose. 

Safety Concerns

  • The most common side effects of Sporanox include headaches, nausea, diarrhea, stomach pain, and rashes. These are generally mild and may resolve with continued use.
  • Less common but serious side effects may include liver damage (signs include yellowing of the skin or eyes), heart failure, and severe allergic reactions (e.g., swelling of the face or difficulty breathing). If any of these occur, get medical help right away. 
  • Itraconazole can interact with several other medications, including those used for heart conditions (e.g., certain calcium channel blockers and antiarrhythmic drugs), statins, and benzodiazepines. It is essential to inform your healthcare provider about all the medications you are taking. 
  • Sporanox may affect liver function. Regular monitoring of liver enzymes is recommended during treatment, especially in long-term use.
  • Itraconazole can lead to or worsen heart failure. Patients with a history of heart conditions should be regularly monitored. 

Avoid Sporanox (Itraconazole) If

  • Avoid using Sporanox if you are allergic to itraconazole or any of its components. 
  • Avoid Sporanox if you have liver disease, particularly active liver problems, as it can worsen liver damage.
  • Do not take Sporanox if you have a history of heart failure or are at risk for heart problems, as it can negatively affect heart function.
  • Itraconazole is classified as pregnancy category C, meaning it should only be used during pregnancy if absolutely necessary. It is also excreted in breast milk and should be avoided while breastfeeding.
  • Avoid combining Sporanox with certain medications, such as those for arrhythmias (e.g., quinidine, dofetilide), certain statins, or any other drugs that interact with itraconazole. Always let your healthcare provider know about any other medications you are taking.


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