Manufactured By : Authorized Indian and UK Generic
℞ Prescription Required
Product Details
Corlanor
Save over 85% with brand and 92% with generic Corlanor.
Corlanor is called Procoralan or Coralan in Europe.
Information about Corlanor (Ivabradine)
Corlanor is a brand name for ivabradine, a medication used to treat certain heart conditions. It specifically targets heart rate without affecting blood pressure, making it useful for managing chronic heart conditions where controlling the heart rate is beneficial.
Product Highlights
Used in patients with chronic heart failure with a reduced ejection fraction (HFrEF) to lower heart rate and improve symptoms.
Helps to manage stable angina by reducing the heart rate, which can decrease the heart’s oxygen demand and reduce angina episodes.
Key Ingredient
Ivabradine
Key Benefits
Effectively reduces heart rate without affecting blood pressure or cardiac contractility, which is particularly beneficial in heart failure and angina.
In chronic heart failure, it can reduce symptoms like shortness of breath and improve exercise capacity.
Provides an option for heart rate management in patients with stable blood pressure.
Direction of Use
Corlanor is typically taken twice daily, with or without food. The dosage is usually adjusted based on the patient’s heart rate and response to treatment.
The tablets should be ingested whole with a sufficient amount of water. They should not be broken, chewed, or crushed.
Regular monitoring of heart rate and other parameters may be required to ensure effectiveness and safety.
Dose Adjustment for Adults:
Heart Rate
Dose Adjustment
> 60 bpm
Increase dose by 2.5 mg (given twice daily) up to a maximum dose of 7.5 mg twice daily
50-60 bpm
Maintain dose
< 50 bpm or signs and symptoms of bradycardia
Decrease dose by 2.5 mg (given twice daily); if current dose is 2.5 mg twice daily, discontinue therapy
Safety Concerns
Common side effects include bradycardia (slow heart rate), hypertension, and visual disturbances. Serious side effects might include severe bradycardia and arrhythmias.
Ivabradine may interact with other medications, including those that affect the CYP3A4 enzyme system, which can alter ivabradine levels and increase the risk of side effects.
Some patients may experience visual disturbances, such as seeing flashes of light, due to the drug’s effect on the retina.
Avoid Corlanor (Ivabradine) If
It should be avoided in patients with severe bradycardia or heart block, where the heart rate is already too slow.
Corlanor is not recommended for patients experiencing acute decompensated heart failure.
Caution is required in patients with severe liver impairment, as the drug is metabolized by the liver.
Avoid in patients taking strong CYP3A4 inhibitors or inducers, as these can significantly impact ivabradine levels and effectiveness.
