Information about Metopirone (Metyrapone)
Metopirone is a medication used primarily in the diagnosis and treatment of conditions related to adrenal function. It works by inhibiting the enzyme 11-beta-hydroxylase, which plays a key role in cortisol synthesis, thereby lowering cortisol levels in the body.
Product Highlights
- Metopirone is primarily indicated for:
- Diagnostic evaluation of adrenal insufficiency, particularly in the context of Cushing's syndrome.
- Treatment of adrenal insufficiency or certain conditions related to excess cortisol production.
Key Ingredient
Key Benefits
- Helps assess adrenal function and diagnose disorders related to cortisol production.
- Can be useful in managing specific types of adrenal insufficiency.
- Provides a non-invasive option for evaluating the hypothalamic-pituitary-adrenal (HPA) axis.
Direction of Use
- Take Metopirone exactly as prescribed by your healthcare provider.
- The dosage may vary based on the diagnosis and individual response.
- It can be taken with or without food, but it's important to maintain consistency in how it’s administered.
Safety Concerns
- Common side effects may include nausea, dizziness, headaches, and digestive issues.
- Serious side effects can include adrenal crisis, particularly if the medication is stopped suddenly or not taken as directed.
- Monitoring of adrenal function and cortisol levels may be required during treatment.
Avoid Metopirone (Metyrapone) If
- You have a known hypersensitivity to metyrapone or any of its components.
- You are pregnant or breastfeeding without prior consultation with your healthcare provider.
- You have severe adrenal insufficiency or conditions that may worsen with decreased cortisol levels.
- You have certain medical conditions, such as uncontrolled hypertension, without discussing with a healthcare professional.