Information about Synarel Nasal Spray (Nafarelin)
Synarel nasal spray contains nafarelin, a synthetic analogue of gonadotropin-releasing hormone (GnRH). It is mainly used to treat hormone-related conditions by modifying the release of specific hormones. Nafarelin works by suppressing the secretion of estrogen and testosterone, helping manage conditions such as endometriosis and precocious puberty.
Product Highlights
- Synarel nasal spray is indicated for:
- A condition in which tissue similar to the uterine lining grows outside the uterus, leading to pain and potential infertility.
- A condition in which puberty starts unusually early, before the age of 8 in girls and 9 in boys.
- Occasionally used for other disorders as prescribed by a healthcare provider, depending on clinical judgment.
Key Ingredient
Key Benefits
- Helps lower estrogen and testosterone levels, providing relief from hormone-driven conditions like endometriosis.
- Delays the onset of puberty in children with central precocious puberty.
- By regulating hormones, Synarel helps to manage symptoms, reduce pain, and improve fertility in those with hormone-sensitive conditions.
- Delivered via a nasal spray, providing a non-invasive, easy-to-use alternative to injections.
Direction of Use
- Gently blow your nose before using the nasal spray.
- Insert the nasal spray nozzle into one nostril while holding the opposite nostril closed.
- Spray the prescribed dose into the nostril as directed by your healthcare provider.
- Use the nasal spray as prescribed, typically once or twice daily.
- Adhere to your healthcare provider’s instructions for the precise dosage and timing.
- After each use, clean the nasal spray nozzle to avoid any blockages.
Safety Concerns
- Due to the reduction in estrogen or testosterone, users may experience symptoms like hot flashes.
- Long-term use of Nafarelin can lead to a decrease in bone density, increasing the risk of fractures.
- Hormonal changes may cause mood swings, depression, or irritability.
- In some cases, nafarelin treatment can cause ovarian cysts, especially in women with endometriosis.
- Possible headaches, nausea, vaginal dryness (in women), or decreased libido.
Avoid Synarel Nasal Spray (Nafarelin) If
- You are allergic to nafarelin or any of the ingredients in the nasal spray.
- You are pregnant or breastfeeding, as it is not recommended during pregnancy or lactation.
- You have a history of certain hormone-sensitive cancers, such as breast cancer, unless explicitly advised by your healthcare provider.
- You have undiagnosed abnormal vaginal bleeding, which should be evaluated before use.
- You have a history of osteoporosis or other bone disorders, as long-term use can worsen bone health.
