Gattex is called Revestive in Europe.
Information about Gattex (Teduglutide)
Gattex is a synthetic analog of human glucagon-like peptide-2 (GLP-2) used to treat patients with short bowel syndrome (SBS) who are dependent on parenteral nutrition (PN). It helps improve intestinal absorption and reduces the need for intravenous nutrition.
Product Highlights
- Management of short bowel syndrome in patients who require parenteral nutrition.
- Aims to increase intestinal absorption and promote bowel adaptation.
Key Ingredient
Key Benefits
- Increases intestinal absorption of nutrients and fluids.
- Reduces the volume and duration of parenteral nutrition needed.
- Can improve quality of life for patients with SBS.
Direction of Use
- Administered through a subcutaneous injection, typically in the abdominal area.
- Dosage is typically 0.05 mg/kg once daily; dosage adjustments may be made based on clinical response.
Safety Concerns
- Possible side effects include gastrointestinal issues (e.g., nausea, abdominal pain), injection site reactions, and potential for increased risk of neoplasms due to growth-promoting effects.
- Monitor for signs of pancreatitis and gastrointestinal obstruction.
Avoid Gattex (Teduglutide) If
- You have a history of allergic reactions to teduglutide or any of its components.
- You have active gastrointestinal malignancies.
- You have a history of pancreatitis or significant pancreatic disease.
- You are pregnant or breastfeeding without first consulting a healthcare provider.
