Information about Copegus (Ribavirin)
Copegus is a brand name for Ribavirin, an antiviral medication used primarily in the treatment of certain types of chronic hepatitis C virus (HCV) infections. It is usually prescribed in combination with other antiviral drugs, such as peginterferon alfa, rather than used alone. Ribavirin works by inhibiting viral RNA synthesis, thereby limiting the virus's ability to replicate and spread.
Product Highlights
Chronic Hepatitis C infection (particularly genotypes where Ribavirin + interferon combination has shown effectiveness)
Occasionally used off-label for other viral infections (e.g., some viral hemorrhagic fevers under expert supervision)
Key Ingredient
Key Benefits
- Enhances the effectiveness of interferon-based therapy in managing chronic HCV
- Helps reduce liver inflammation and the risk of liver damage due to long-term HCV infection
- When used appropriately, can contribute to achieving sustained virologic response (SVR), which is considered a functional cure for hepatitis C
Direction of Use
- Varies based on body weight, usually 800 mg to 1200 mg per day in divided doses
- Oral, with food to improve absorption
- Typically 24–48 weeks depending on HCV genotype and response to treatment
- Always follow the prescribing healthcare provider's instructions and never self-adjust the dosage
Safety Concerns
- Extremely high teratogenic risk — can cause severe birth defects or fetal death. Pregnancy must be avoided during treatment and for at least 6 months afterward (both male and female patients must use effective contraception).
- Fatigue, anemia, nausea, rash, irritability, insomnia
- Hemolytic anemia, depression, suicidal ideation (especially when used with interferon), worsening of heart disease
- Regular blood tests are required to monitor red blood cell counts and liver function during treatment
Avoid Copegus (Ribavirin) If
- You are pregnant or planning to become pregnant
- Your partner is pregnant (for male patients taking the drug)
- You have a history of severe heart disease, particularly with anemia
- You have autoimmune hepatitis
- You are allergic to Ribavirin or any of the excipients in Copegus
- You have severe kidney disease (without dose adjustment or monitoring)
