Afinitor Disperz is called Votubia in Europe.
Information about Afinitor Disperz (Everolimus):
It is primarily used in the treatment of hormone receptor-positive, HER2-negative breast cancer.
Afinitor Disperz is a specific formulation of Everolimus designed for oral administration.
AFINITOR is prescribed for adult patients diagnosed with progressive pancreatic neuroendocrine tumors (PNET) that are unrespectable, locally advanced, or metastatic.
Product Highlights
- Afinitor Disperz comes in the form of dispersible tablets, which are intended to be dispersed in water and swallowed. This formulation is particularly convenient for patients who have difficulty swallowing whole tablets.
- AFINITOR is prescribed for adult patients with advanced RCC who have not responded to prior treatment with sunitinib or sorafenib.
- AFINITOR is used to treating adult patients with renal angiomyolipoma and TSC who do not need immediate surgery.
Direction of Use:
- Administration: Afinitor Disperz tablets should be dispersed in approximately 20 mL of water. Stir the mixture gently and drink it immediately after dispersion. Rinse the glass with more water and drink to ensure the entire dose is consumed.
- Dosage: The dosage and schedule of Afinitor Disperz are determined by the healthcare provider based on factors such as the specific condition being treated, the patient's medical history, and other medications they may be taking. It is crucial to follow the prescribed dosage and administration instructions carefully to achieve optimal treatment outcomes.
Key Benefits
- Afinitor Disperz is effective in treating advanced breast cancer, pancreatic neuroendocrine tumors (pNET), and advanced renal cell carcinoma (kidney cancer), among others.
- It is also used to manage conditions like tuberous sclerosis complex (TSC), specifically to reduce the size of SEGAs (subependymal giant cell astrocytomas) and alleviate associated symptoms like hydrocephalus.
Key Ingredient:
- Everolimus
- Butylated hydroxytoluene
- Colloidal silicon dioxide
- Crospovidone, hypromellose
- Lactose monohydrate
- Magnesium stearate
- Mannitol
- Microcrystalline cellulose
Safety Concern
- Common Side Effects: These may include fatigue, nausea, diarrhea, skin rash, and decreased appetite.
- Serious Side Effects: These can include severe allergic reactions, infections, and changes in kidney function. Regular monitoring by healthcare providers is crucial to manage these risks.
Avoid Taking Afinitor Disperz (Everolimus) If:
- Avoid if allergic to Everolimus or any ingredients in the formulation.
- It should not be used if there are uncontrolled infections.
- Use caution or avoid if there is severe liver impairment.
- Afinitor Disperz may harm the fetus or breastfeeding infant; thus, its use is generally avoided during pregnancy and breastfeeding.
