Category Details

Huntington's Disease

Huntington's disease (HD) is a progressive, hereditary neurodegenerative disorder characterized by the gradual deterioration of motor control, cognitive function, and emotional stability. Caused by a mutation in the HTT gene, HD typically manifests in mid-adulthood and leads to a range of debilitating symptoms, including involuntary movements, changes in behavior, and cognitive decline. Advances in Huntington's disease medicine have focused on developing symptomatic treatments to manage motor and psychiatric symptoms, with options such as antipsychotics, antidepressants, and medications for movement disorders. Additionally, groundbreaking research is underway to explore disease-modifying therapies, including gene silencing and other innovative approaches aimed at slowing disease progression. As our understanding of the underlying mechanisms of HD continues to evolve, these advancements hold promise for improving the quality of life for individuals affected by this challenging condition and ultimately finding effective treatments.

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