Schizophrenia is a complex and often debilitating mental health disorder characterized by a range of symptoms, including hallucinations, delusions, disorganized thinking, and emotional flatness. These symptoms can significantly impact an individual's ability to function in everyday life, affecting relationships, work, and overall well-being. While the exact cause of schizophrenia remains unclear, a combination of genetic, environmental, and neurobiological factors is believed to play a role. Fortunately, advancements in psychiatric medicine have led to the development of various treatment options aimed at managing the disorder. Antipsychotic medications, which can be categorized into first-generation (typical) and second-generation (atypical) drugs, are central to treatment plans. These medications work by modulating neurotransmitter activity in the brain, helping to reduce symptoms and improve quality of life. In this overview, we will explore the different classes of medications available for schizophrenia, their mechanisms of action, and their role in the comprehensive management of this challenging condition.